eGFR Sec CKD-EPI Calculator

eGFR Sec CKD-EPI Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What Is The eGFR Sec CKD-EPI Equation?

The eGFR Sec CKD-EPI equation is a modified version of the CKD-EPI equation that estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex. It provides an accurate assessment of kidney function with updated coefficients.

2. How Does The Calculator Work?

The calculator uses the eGFR Sec CKD-EPI equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: This equation provides improved accuracy in estimating kidney function with optimized coefficients for different demographic groups.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is essential for diagnosing chronic kidney disease, monitoring disease progression, and determining appropriate treatment strategies.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. Ensure all values are valid (creatinine > 0, age between 1-120 years).

5. Frequently Asked Questions (FAQ)

Q1: What Is The Difference Between eGFR Sec CKD-EPI And Standard CKD-EPI?
A: eGFR Sec CKD-EPI uses updated coefficients (142, -1.200, 0.9938, 1.012) that may provide improved accuracy in certain populations.

Q2: What Are Normal eGFR Values?
A: Normal eGFR is generally ≥90 mL/min/1.73m². Values below 60 mL/min/1.73m² for 3+ months may indicate chronic kidney disease.

Q3: When Should Serum Creatinine Be Measured?
A: Morning fasting samples are preferred, but random samples are acceptable. Avoid testing after high-protein meals or intense physical activity.

Q4: Are There Limitations To This Equation?
A: This equation may be less accurate in extreme age groups, pregnant women, individuals with muscle wasting, or those with rapidly changing kidney function.

Q5: Can This Calculator Be Used For Medication Dosing?
A: While useful for screening, precise medication dosing may require measured GFR in specific clinical situations.