DaVita eGFR using CKD-EPI 2021:
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The DaVita eGFR Calculator uses the CKD-EPI 2021 equation to estimate glomerular filtration rate (GFR) from serum creatinine, age, and sex. This updated equation provides enhanced accuracy in assessing kidney function compared to previous versions.
The calculator uses the DaVita CKD-EPI 2021 equation:
Where:
Explanation: This equation incorporates updated coefficients and exponents based on recent research, providing more precise GFR estimates across different population groups.
Details: Accurate GFR estimation is essential for early detection of chronic kidney disease, monitoring disease progression, and making informed clinical decisions about treatment and medication dosing.
Tips: Enter serum creatinine in mg/dL, age in years, and select gender. Ensure all values are valid (creatinine > 0, age between 1-120 years) for accurate results.
Q1: What makes the DaVita 2021 equation different?
A: The DaVita 2021 equation uses updated coefficients (142, -1.200, 0.9938) and gender-specific alpha values for improved accuracy across diverse populations.
Q2: What are the clinical implications of eGFR results?
A: eGFR values help classify kidney disease stages: ≥90 (normal), 60-89 (mild reduction), 30-59 (moderate), 15-29 (severe), and <15 (kidney failure).
Q3: How often should eGFR be monitored?
A: Frequency depends on clinical context: annually for at-risk individuals, more frequently for those with established kidney disease or changing conditions.
Q4: Are there patient populations where this equation may be less accurate?
A: Accuracy may be reduced in extremes of age, body composition, amputees, pregnant women, and those with rapidly changing kidney function or muscle mass.
Q5: Can this calculator be used for pediatric patients?
A: No, this equation is validated for adults (18+ years). Pediatric GFR estimation requires specialized equations accounting for growth and development.