eGFR Calculator with Race

CKD-EPI Equation:

\[ eGFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{age} \times (1.018 \text{ if female}) \times (1.159 \text{ if black}) \]

Serum Creatinine (Scr):

mg/dL

Age:

years

Gender:

Race:

Estimated GFR (eGFR):

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1. What Is eGFR Calculator with Race?

The eGFR Calculator with Race uses the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation to estimate glomerular filtration rate (GFR) from serum creatinine, age, sex, and race. This calculator provides a more accurate assessment of kidney function, particularly incorporating race as a factor in the calculation.

2. How Does the Calculator Work?

The calculator uses the CKD-EPI equation including race:

\[ eGFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{age} \times (1.018 \text{ if female}) \times (1.159 \text{ if black}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.329 (female) or -0.411 (male)
\( age \) — Age in years
1.018 — Female multiplier
1.159 — Black race multiplier

Explanation: This equation accounts for the non-linear relationship between creatinine and GFR, with specific coefficients for different demographic groups including race considerations.

3. Importance of eGFR Calculation

Details: Accurate GFR estimation that includes race factors is crucial for diagnosing chronic kidney disease, determining disease stage, and guiding appropriate treatment decisions across diverse populations.

4. Using the Calculator

Tips: Enter serum creatinine in mg/dL, age in years, select gender and race. All values must be valid (creatinine > 0, age between 1-120). The race factor is specifically included to provide more accurate estimates for different populations.

5. Frequently Asked Questions (FAQ)

Q1: Why include race in eGFR calculation?
A: Race is included as studies have shown differences in muscle mass and creatinine metabolism between racial groups, which affects GFR estimation accuracy.

Q2: What are normal eGFR values?
A: Normal is generally ≥90 mL/min/1.73m², though values naturally decline with age. Below 60 for 3+ months indicates chronic kidney disease.

Q3: How does race affect eGFR results?
A: The Black race multiplier (1.159) increases the calculated eGFR by approximately 16% for Black individuals compared to other races.

Q4: Are there limitations to race-adjusted equations?
A: Yes, race is a social construct and may not accurately represent biological differences. Some institutions are moving toward race-neutral equations.

Q5: Should this calculator be used for all populations?
A: While widely used, clinicians should consider individual patient factors and local guidelines when interpreting results.