eGFR Calculator Without Cystatin C

CKD-EPI Equation Without Cystatin C:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{Age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

Unit Converter ▲

Unit Converter ▼

From:	To:

1. What Is eGFR Calculator Without Cystatin C?

The eGFR Calculator Without Cystatin C estimates glomerular filtration rate (GFR) using the CKD-EPI equation based solely on serum creatinine, age, and gender. This version does not incorporate cystatin C measurements, providing a creatinine-only assessment of kidney function.

2. How Does The Calculator Work?

The calculator uses the CKD-EPI equation without cystatin C:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{Age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( Age \) — Age in years
1.012 — Female multiplier

Explanation: This equation provides GFR estimation using creatinine values only, with optimized coefficients for different demographic groups.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is essential for detecting chronic kidney disease, monitoring kidney function, and guiding clinical decisions regarding medication dosing and treatment planning.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. Ensure all values are valid (creatinine > 0, age between 1-120 years).

5. Frequently Asked Questions (FAQ)

Q1: What Is The Difference Between This And Cystatin C Equations?
A: This calculator uses only serum creatinine, while cystatin C equations incorporate an additional biomarker that may provide more accurate GFR estimation in certain populations.

Q2: When Is Creatinine-Only eGFR Appropriate?
A: Creatinine-only eGFR is suitable for most routine clinical situations and is widely used for initial kidney function assessment and monitoring.

Q3: What Are The Limitations Of Creatinine-Only eGFR?
A: Creatinine levels can be affected by muscle mass, diet, and certain medications, which may limit accuracy in some individuals.

Q4: Should This Be Used For Elderly Patients?
A: While applicable, creatinine-based equations may be less accurate in elderly patients with reduced muscle mass; clinical correlation is important.

Q5: How Often Should eGFR Be Calculated?
A: Frequency depends on clinical context, but typically annually for monitoring stable patients or more frequently for those with known kidney disease.