eGFR Calculator UK Kidney

UK Kidney eGFR Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What Is The UK Kidney eGFR Equation?

The UK Kidney eGFR equation estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex. This equation is specifically validated for UK populations and provides accurate assessment of kidney function.

2. How Does The Calculator Work?

The calculator uses the UK Kidney eGFR equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: The equation accounts for non-linear relationship between creatinine and GFR, with different coefficients for different demographic groups, specifically optimized for UK populations.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is crucial for diagnosing chronic kidney disease, determining disease stage, and guiding medication dosing in UK healthcare settings.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. All values must be valid (creatinine > 0, age between 1-120).

5. Frequently Asked Questions (FAQ)

Q1: Why Use UK Kidney Equation Instead Of CKD-EPI?
A: The UK Kidney equation is specifically validated and optimized for UK populations, providing better accuracy for local demographic characteristics.

Q2: What Are Normal eGFR Values For UK Population?
A: Normal is generally ≥90 mL/min/1.73m², though values decline with age. Below 60 for 3+ months indicates CKD according to UK guidelines.

Q3: When Should Creatinine Be Measured In UK Practice?
A: Morning fasting sample is ideal, but random samples are acceptable in routine UK clinical practice.

Q4: Are There Limitations To This Equation In UK Setting?
A: Less accurate in extremes of age/weight, amputees, pregnant women, and those with rapidly changing kidney function in UK populations.

Q5: Should This Be Used For Drug Dosing In UK?
A: For precise drug dosing in UK healthcare, measured GFR may be needed in certain high-risk populations.