CKD-EPI Equation:
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The eGFR Calculator Race estimates glomerular filtration rate (GFR) using the CKD-EPI equation that incorporates race as a factor. This calculator provides accurate kidney function assessment based on serum creatinine, age, sex, and race.
The calculator uses the CKD-EPI equation:
Where:
Explanation: This equation accounts for demographic differences in creatinine production and muscle mass, providing more personalized eGFR estimates.
Details: Accurate GFR estimation is essential for chronic kidney disease diagnosis, staging, and appropriate medication dosing decisions.
Tips: Enter serum creatinine in mg/dL, age in years, select gender and race. Ensure all values are valid (creatinine > 0, age between 1-120 years).
Q1: Why Include Race In eGFR Calculation?
A: Race is included because studies show differences in creatinine metabolism and muscle mass across racial groups, affecting eGFR accuracy.
Q2: What Are Normal eGFR Values?
A: Normal eGFR is generally ≥90 mL/min/1.73m². Values below 60 for 3+ months indicate chronic kidney disease.
Q3: When Should Creatinine Be Measured?
A: Morning fasting samples are preferred, but random samples are acceptable. Avoid testing after high-protein meals or strenuous exercise.
Q4: Are There Limitations To Race-Based Equations?
A: Recent discussions highlight concerns about race-based medicine. Some institutions are transitioning to race-neutral equations.
Q5: Should This Be Used For Drug Dosing?
A: For precise drug dosing, especially with narrow therapeutic windows, measured GFR may be necessary in specific populations.