eGFR Calculator Pathlab

Pathlab eGFR Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What Is The eGFR Calculator Pathlab?

The Pathlab eGFR equation estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex. This specific equation is optimized for laboratory use and provides accurate assessment of kidney function in clinical settings.

2. How Does The Calculator Work?

The calculator uses the Pathlab eGFR equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: This equation provides a refined estimate of kidney function using optimized coefficients for laboratory analysis.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is essential for diagnosing kidney disease stages, monitoring kidney function over time, and guiding appropriate clinical management decisions.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. Ensure all values are valid (creatinine > 0, age between 1-120 years) for accurate results.

5. Frequently Asked Questions (FAQ)

Q1: What Makes The Pathlab Equation Different?
A: The Pathlab eGFR equation uses specific coefficients (142, -1.200, 0.9938) optimized for laboratory testing environments and standardized creatinine measurements.

Q2: What Are Normal eGFR Values?
A: Normal eGFR is generally ≥90 mL/min/1.73m². Values below 60 mL/min/1.73m² persisting for 3+ months indicate chronic kidney disease.

Q3: When Should Creatinine Be Measured?
A: For optimal accuracy, measure serum creatinine in morning fasting samples. Avoid testing after high-protein meals or strenuous physical activity.

Q4: Are There Limitations To This Equation?
A: This equation may be less accurate in elderly patients, extremes of body size, pregnant women, and individuals with rapidly changing kidney function.

Q5: Can This Be Used For Medication Dosing?
A: While useful for screening, precise medication dosing may require measured GFR in specific patient populations or for drugs with narrow therapeutic windows.