eGFR Calculator No Race

CKD-EPI 2021 Equation (Without Race Factor):

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What is the CKD-EPI 2021 Equation?

The CKD-EPI 2021 equation estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex without using race as a factor. This updated version provides a more equitable assessment of kidney function across all populations.

2. How Does the Calculator Work?

The calculator uses the CKD-EPI 2021 equation without race factor:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: This equation eliminates race-based adjustments, providing a more equitable approach to kidney function assessment while maintaining accuracy across diverse populations.

3. Importance of eGFR Calculation

Details: Accurate GFR estimation is crucial for diagnosing chronic kidney disease, determining disease stage, guiding medication dosing, and monitoring kidney function over time without racial bias.

4. Using the Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. All values must be valid (creatinine > 0, age between 1-120). No race selection is required as this calculator uses the race-neutral equation.

5. Frequently Asked Questions (FAQ)

Q1: Why was race removed from the CKD-EPI equation?
A: Race was removed to eliminate racial bias in kidney function assessment and provide more equitable healthcare across all populations.

Q2: How accurate is the race-neutral equation?
A: The CKD-EPI 2021 equation without race factor maintains good accuracy while removing potentially harmful racial categorization from medical decision-making.

Q3: What are normal eGFR values?
A: Normal is generally ≥90 mL/min/1.73m², though values decline with age. Below 60 for 3+ months indicates CKD.

Q4: When should creatinine be measured?
A: Morning fasting sample is ideal, but random samples are acceptable. Avoid testing after meat-heavy meals or vigorous exercise.

Q5: Are there limitations to this equation?
A: Less accurate in extremes of age/weight, amputees, pregnant women, and those with rapidly changing kidney function.