eGFR Calculator Malaysia

Malaysia eGFR Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What is the Malaysia eGFR Calculator?

The Malaysia eGFR Calculator uses the CKD-EPI 2021 equation specifically validated for the Malaysian population. It estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex, providing accurate assessment of kidney function tailored to local demographics.

2. How Does the Calculator Work?

The calculator uses the Malaysia CKD-EPI 2021 equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: This equation is specifically calibrated for the Malaysian population and accounts for the non-linear relationship between creatinine and GFR with demographic-specific coefficients.

3. Importance of eGFR Calculation

Details: Accurate GFR estimation is crucial for diagnosing chronic kidney disease in the Malaysian population, determining disease stage, and guiding appropriate treatment and medication dosing specific to local healthcare needs.

4. Using the Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. All values must be valid (creatinine > 0, age between 1-120). This calculator is specifically designed for use with Malaysian patient data.

5. Frequently Asked Questions (FAQ)

Q1: Why use the Malaysia-specific CKD-EPI equation?
A: The Malaysia CKD-EPI 2021 equation is specifically validated for the Malaysian population, providing more accurate results that account for local demographic and genetic factors.

Q2: What are normal eGFR values for Malaysians?
A: Normal is generally ≥90 mL/min/1.73m², though values naturally decline with age. Below 60 for 3+ months indicates chronic kidney disease.

Q3: When should creatinine be measured in Malaysia?
A: Morning fasting sample is ideal, but random samples are acceptable. Avoid testing after heavy meals or vigorous exercise for accurate results.

Q4: Are there limitations to this equation in Malaysia?
A: As with all equations, it may be less accurate in extremes of age/weight, amputees, pregnant women, and those with rapidly changing kidney function.

Q5: Is this calculator suitable for all ethnic groups in Malaysia?
A: Yes, this equation has been validated across the multi-ethnic Malaysian population including Malay, Chinese, and Indian ethnicities.