eGFR Calculator African American

CKD-EPI Equation:

\[ eGFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{age} \times (1.018 \text{ if female}) \times (1.159 \text{ if African American}) \]

Serum Creatinine (Scr):

mg/dL

Age:

years

Gender:

Race:

Estimated GFR (eGFR):

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1. What Is The eGFR Calculator African American?

The eGFR Calculator African American uses the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation specifically calibrated for African American individuals. It estimates glomerular filtration rate (GFR) from serum creatinine, age, sex, and incorporates the race factor of 1.159 for African American population.

2. How Does The Calculator Work?

The calculator uses the CKD-EPI equation with African American adjustment:

\[ eGFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{age} \times (1.018 \text{ if female}) \times (1.159 \text{ if African American}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.329 (female) or -0.411 (male)
\( age \) — Age in years
1.018 — Female multiplier
1.159 — African American race multiplier

Explanation: The equation accounts for the higher muscle mass and creatinine production in African American individuals, providing more accurate GFR estimation for this population.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is crucial for diagnosing chronic kidney disease in African American populations, determining disease stage, and guiding appropriate treatment and medication dosing.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, select gender and specify African American race. All values must be valid (creatinine > 0, age between 1-120).

5. Frequently Asked Questions (FAQ)

Q1: Why is there a specific calculator for African American individuals?
A: African American individuals typically have higher muscle mass and creatinine generation rates, requiring adjustment for accurate GFR estimation.

Q2: What is the significance of the 1.159 multiplier?
A: The 1.159 multiplier accounts for the higher average creatinine levels in African American individuals due to increased muscle mass.

Q3: Are there normal eGFR values for African American populations?
A: Normal values are generally ≥90 mL/min/1.73m², but the calculation adjusts for population-specific characteristics.

Q4: When should this specific calculator be used?
A: Use this calculator specifically for African American individuals to ensure accurate kidney function assessment.

Q5: Are there limitations to using race-based equations?
A: While useful for population-level accuracy, individual variations exist. Clinical judgment should always complement calculated results.