What Is GFR Calculation CKD-EPI In Blood Test

CKD-EPI Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What Is GFR Calculation CKD-EPI In Blood Test?

The CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex. It provides an accurate assessment of kidney function in blood test results, explaining how GFR is calculated using the CKD-EPI formula.

2. How Does The Calculator Work?

The calculator uses the CKD-EPI equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( eGFR \) — Estimated Glomerular Filtration Rate (mL/min/1.73m²)
\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 if female, 0.9 if male (unitless)
\( \alpha \) — -0.241 if female, -0.302 if male (unitless)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: The equation accounts for non-linear relationship between creatinine and GFR, with different coefficients for different demographic groups.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is crucial for diagnosing chronic kidney disease, determining disease stage, monitoring kidney function over time, and guiding clinical decisions in blood test interpretations.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. All values must be valid (creatinine > 0, age between 1-120). The calculator will provide the estimated GFR based on the CKD-EPI equation.

5. Frequently Asked Questions (FAQ)

Q1: What does GFR represent in blood tests?
A: GFR (Glomerular Filtration Rate) measures how well your kidneys are filtering waste from your blood, providing a key indicator of kidney function.

Q2: Why is the CKD-EPI equation used?
A: The CKD-EPI equation provides more accurate GFR estimates across a wider range of kidney function levels compared to older equations.

Q3: What are normal eGFR ranges?
A: Normal eGFR is generally ≥90 mL/min/1.73m². Values below 60 for 3+ months may indicate chronic kidney disease.

Q4: How does age affect eGFR?
A: GFR naturally declines with age, so age-adjusted interpretations are important for accurate assessment.

Q5: When should this calculation be used?
A: This calculation should be used when interpreting blood test results to assess kidney function and screen for kidney disease.