What Is GFR Calculated Abbreviated MDRD UK

Abbreviated MDRD Equation:

\[ eGFR = 175 \times Scr^{-1.154} \times Age^{-0.203} \times (0.742 \text{ if female}) \times (1.212 \text{ if Black}) \]

Serum Creatinine (Scr):

mg/dL

Age:

years

Gender:

Race:

Estimated GFR (eGFR):

Unit Converter ▲

Unit Converter ▼

From:	To:

1. What Is GFR Calculated Abbreviated MDRD UK?

The Abbreviated MDRD (Modification of Diet in Renal Disease) equation estimates glomerular filtration rate (GFR) from serum creatinine, age, sex, and race. This version is commonly used in UK clinical practice for assessing kidney function.

2. How Does The Calculator Work?

The calculator uses the Abbreviated MDRD equation:

\[ eGFR = 175 \times Scr^{-1.154} \times Age^{-0.203} \times (0.742 \text{ if female}) \times (1.212 \text{ if Black}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( Age \) — Age in years
0.742 — Female multiplier
1.212 — Black race multiplier

Explanation: The equation provides an estimate of kidney function based on serum creatinine levels adjusted for age, gender, and race factors.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is essential for detecting chronic kidney disease, monitoring disease progression, and adjusting medication dosages based on renal function.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, select gender and race. All values must be valid (creatinine > 0, age between 1-120 years).

5. Frequently Asked Questions (FAQ)

Q1: What Is The Difference Between MDRD And CKD-EPI Equations?
A: The MDRD equation tends to underestimate GFR in patients with normal or near-normal kidney function, while CKD-EPI provides more accurate estimates across the full range of kidney function.

Q2: Why Is The MDRD Equation Still Used In The UK?
A: The MDRD equation remains widely used in the UK due to its established validation in local populations and consistency with historical data.

Q3: What Are The Limitations Of The MDRD Equation?
A: The equation may be less accurate in elderly patients, those with extreme body mass indices, and populations with different muscle mass characteristics.

Q4: How Often Should eGFR Be Monitored?
A: Frequency depends on clinical context, but typically annually for stable patients and more frequently for those with known kidney disease or risk factors.

Q5: Can This Calculator Be Used For Children?
A: No, the MDRD equation is validated for adults only. Pediatric patients require specialized equations accounting for body surface area.