UK Kidney Org eGFR Calculator

UK Kidney Association CKD-EPI 2021 Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

Unit Converter ▲

Unit Converter ▼

From:	To:

1. What is the UK Kidney Association CKD-EPI 2021 Equation?

The UK Kidney Association CKD-EPI 2021 equation estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex. This updated version provides improved accuracy for the UK population and is recommended for clinical use in the United Kingdom.

2. How Does the Calculator Work?

The calculator uses the UK Kidney Association CKD-EPI 2021 equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: This equation incorporates updated coefficients optimized for the UK population, providing more accurate GFR estimation in clinical practice.

3. Importance of eGFR Calculation

Details: Accurate GFR estimation is essential for diagnosing chronic kidney disease, monitoring disease progression, and determining appropriate medication dosages in UK healthcare settings.

4. Using the Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. All values must be valid (creatinine > 0, age between 1-120). This calculator is specifically validated for use in the UK population.

5. Frequently Asked Questions (FAQ)

Q1: Why use the UK Kidney Association CKD-EPI 2021 equation?
A: This equation is specifically validated and optimized for the UK population, providing improved accuracy compared to previous versions for British patients.

Q2: What are the key differences from standard CKD-EPI?
A: The UK version uses updated coefficients (142, -1.200, 0.9938, 1.012) that are specifically calibrated for the UK demographic characteristics.

Q3: Is this calculator suitable for all ethnicities in the UK?
A: While optimized for the general UK population, specific adjustments may be needed for certain ethnic groups as per local clinical guidelines.

Q4: When was this equation introduced?
A: The UK Kidney Association CKD-EPI 2021 equation was introduced in 2021 as an update to previous GFR estimation methods used in the UK.

Q5: Are there specific clinical guidelines for using this equation in the UK?
A: Yes, this equation is recommended in current UK clinical guidelines for chronic kidney disease management and drug dosing adjustments.