1. What is the Pediatric GFR Calculator?

The Pediatric GFR Calculator using the Bedside Schwartz equation estimates glomerular filtration rate (GFR) in children based on height and serum creatinine measured in µmol/L. This equation is specifically validated for pediatric populations and provides accurate assessment of kidney function in children.

2. How Does the Calculator Work?

The calculator uses the Bedside Schwartz equation:

Where:

• \( Height \) — Height in centimeters (cm)
• \( Scr \) — Serum creatinine in micromoles per liter (µmol/L)
• \( 88.4 \) — Conversion factor from µmol/L to mg/dL
• \( 0.413 \) — Constant coefficient for the equation

Explanation: The equation converts serum creatinine from µmol/L to mg/dL and uses height as a surrogate for muscle mass, providing a reliable estimate of kidney function in pediatric patients.

3. Importance of Pediatric eGFR Calculation

Details: Accurate GFR estimation in children is essential for diagnosing kidney disease, monitoring kidney function in chronic conditions, adjusting medication doses, and evaluating transplant function. Pediatric kidney function assessment requires specialized equations as children's kidney function changes with growth and development.

4. Using the Calculator

Tips: Enter height in centimeters and serum creatinine in µmol/L. Ensure accurate height measurement and use recent creatinine values. The calculator automatically converts µmol/L to mg/dL for the calculation.

5. Frequently Asked Questions (FAQ)

Q1: Why use the Bedside Schwartz equation for children?
A: The Bedside Schwartz equation is specifically developed and validated for pediatric populations, accounting for the relationship between height, muscle mass, and creatinine production in children.

Q2: What age range is this calculator appropriate for?
A: This calculator is designed for children from 1 to 18 years old. For infants under 1 year, different equations may be more appropriate.

Q3: What are normal eGFR values in children?
A: Normal eGFR in children varies by age but generally ranges from 90-140 mL/min/1.73m². Values should be interpreted in context of the child's age and clinical condition.

Q4: Why is height used in pediatric GFR calculations?
A: Height serves as a surrogate for muscle mass, which correlates with creatinine production. This relationship is particularly important in growing children.

Q5: Are there limitations to this equation?
A: The equation may be less accurate in children with extreme body habitus, malnutrition, muscle wasting, or rapidly changing kidney function. It should be used as a screening tool alongside clinical assessment.