1. What is the NKF Pediatric GFR Equation?

The NKF (National Kidney Foundation) pediatric equation estimates glomerular filtration rate (GFR) in children using height and serum creatinine. This simplified formula is specifically designed for pediatric populations and provides a quick assessment of kidney function in children.

2. How Does the Calculator Work?

The calculator uses the NKF pediatric equation:

Where:

• \( Height \) — Height in centimeters (cm)
• \( Scr \) — Serum creatinine in milligrams per deciliter (mg/dL)
• \( 0.413 \) — Conversion constant for pediatric population

Explanation: This equation leverages the relationship between height, creatinine levels, and kidney function in children, providing a standardized estimate normalized to body surface area.

3. Importance of Pediatric eGFR Calculation

Details: Accurate GFR estimation in children is essential for detecting congenital kidney abnormalities, monitoring chronic kidney disease progression, adjusting medication dosages, and evaluating overall renal health during growth and development.

4. Using the Calculator

Tips: Enter height in centimeters and serum creatinine in mg/dL. Ensure accurate height measurement and use recent creatinine values. This calculator is specifically validated for pediatric use (typically 1-18 years).

5. Frequently Asked Questions (FAQ)

Q1: What age range is this equation appropriate for?
A: The NKF pediatric equation is typically used for children aged 1-18 years. For infants under 1 year, different equations may be more appropriate.

Q2: How does this differ from adult GFR equations?
A: Pediatric equations account for growth and development factors, using height as a proxy for body surface area, whereas adult equations typically use age, gender, and race adjustments.

Q3: What are normal eGFR values in children?
A: Normal pediatric eGFR values vary by age but generally range from 90-140 mL/min/1.73m², with higher values in younger children due to increased renal blood flow.

Q4: When should this equation not be used?
A: Avoid using in severely malnourished children, those with amputations, extreme obesity, or rapidly changing kidney function. Also not suitable for neonates.

Q5: How often should eGFR be monitored in children?
A: Frequency depends on clinical indication - for healthy children, annual screening may suffice; for those with kidney disease, more frequent monitoring (every 3-6 months) is recommended.