Paediatric eGFR Calculator UK

Bedside Schwartz Equation:

\[ eGFR = 0.413 \times \frac{Height}{Scr} \]

Estimated GFR (eGFR):

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1. What is the Paediatric eGFR Calculator UK?

The Paediatric eGFR Calculator UK uses the Bedside Schwartz equation to estimate glomerular filtration rate (GFR) in children. This equation is specifically validated for paediatric populations and provides a reliable assessment of kidney function in children using height and serum creatinine measurements.

2. How Does the Calculator Work?

The calculator uses the Bedside Schwartz equation:

\[ eGFR = 0.413 \times \frac{Height}{Scr} \]

Where:

\( Height \) — Height in centimeters (cm)
\( Scr \) — Serum creatinine in milligrams per deciliter (mg/dL)
\( 0.413 \) — Constant coefficient derived from paediatric population studies

Explanation: The equation accounts for the relationship between height, creatinine production, and kidney function in children. Height serves as a proxy for muscle mass, which correlates with creatinine production.

3. Importance of Paediatric eGFR Calculation

Details: Accurate GFR estimation in children is essential for diagnosing kidney disease, monitoring kidney function in chronic conditions, adjusting medication doses, and assessing growth and development impacts on renal function.

4. Using the Calculator

Tips: Enter height in centimeters and serum creatinine in mg/dL. Ensure measurements are recent and accurate. The calculator is specifically designed for paediatric patients (children and adolescents).

5. Frequently Asked Questions (FAQ)

Q1: What age range is this calculator suitable for?
A: The Bedside Schwartz equation is validated for children from 1 to 18 years of age. For infants under 1 year, other equations may be more appropriate.

Q2: Why is height used in paediatric eGFR calculations?
A: Height correlates with muscle mass in children, which determines creatinine production. This makes it a reliable parameter for estimating GFR in the paediatric population.

Q3: What are normal eGFR values for children?
A: Normal eGFR values in children vary by age and body size, but generally range from 90-140 mL/min/1.73m². Values should be interpreted in context with the child's age and clinical condition.

Q4: Are there limitations to this equation?
A: The equation may be less accurate in children with extreme body habitus, muscle wasting diseases, amputations, or rapidly changing kidney function.

Q5: How often should eGFR be monitored in children?
A: Monitoring frequency depends on the clinical situation. Children with known kidney disease may require regular monitoring, while those at risk may need periodic assessment.