1. What is the NKF Pediatric GFR Equation?

The National Kidney Foundation (NKF) pediatric GFR equation estimates glomerular filtration rate in children using height and serum creatinine. This simplified formula provides a quick and reliable assessment of kidney function in pediatric populations.

2. How Does the Calculator Work?

The calculator uses the NKF pediatric equation:

Where:

• \( Height \) — Patient height in centimeters (cm)
• \( Scr \) — Serum creatinine in milligrams per deciliter (mg/dL)
• \( 0.413 \) — Empirical coefficient derived from pediatric population studies

Explanation: The equation utilizes the direct relationship between height and muscle mass, and the inverse relationship between creatinine and kidney function to estimate GFR in children.

3. Importance of Pediatric GFR Calculation

Details: Accurate GFR estimation in children is essential for detecting congenital kidney abnormalities, monitoring chronic kidney disease progression, adjusting medication doses, and evaluating kidney function in various pediatric conditions.

4. Using the Calculator

Tips: Enter height in centimeters and serum creatinine in mg/dL. Ensure accurate height measurement and use recent creatinine values. This calculator is specifically designed for pediatric patients.

5. Frequently Asked Questions (FAQ)

Q1: What age range is this equation appropriate for?
A: This equation is primarily used for children and adolescents, typically from 1 to 18 years of age.

Q2: How does this differ from adult GFR equations?
A: Pediatric equations account for the relationship between height and muscle mass development, which differs significantly from adults.

Q3: What are normal eGFR values in children?
A: Normal pediatric GFR values vary by age and body size, but generally range from 90-140 mL/min/1.73m², with higher values in younger children.

Q4: When should this equation not be used?
A: Avoid using in infants under 1 year, patients with extreme body composition, amputees, or those with rapidly changing kidney function.

Q5: How often should GFR be monitored in children?
A: Frequency depends on clinical indication - typically every 3-12 months for stable CKD, more frequently for acute conditions or medication adjustments.