NKF Pediatric eGFR Calculator

Bedside Schwartz Equation:

\[ eGFR = 0.413 \times \frac{Height}{Scr} \]

Estimated GFR (eGFR):

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1. What is the NKF Pediatric eGFR Calculator?

The NKF Pediatric eGFR Calculator uses the Bedside Schwartz equation to estimate glomerular filtration rate (GFR) in children. This equation is specifically validated for pediatric populations and provides a reliable assessment of kidney function in children using height and serum creatinine measurements.

2. How Does the Calculator Work?

The calculator uses the Bedside Schwartz equation:

\[ eGFR = 0.413 \times \frac{Height}{Scr} \]

Where:

\( eGFR \) — Estimated glomerular filtration rate (mL/min/1.73m²)
\( Height \) — Child's height in centimeters (cm)
\( Scr \) — Serum creatinine in milligrams per deciliter (mg/dL)
\( 0.413 \) — Constant coefficient derived from pediatric population studies

Explanation: The equation accounts for the relationship between height (as a proxy for muscle mass) and creatinine production, providing a more accurate GFR estimation in growing children.

3. Importance of Pediatric eGFR Calculation

Details: Accurate GFR estimation in children is essential for diagnosing and monitoring chronic kidney disease, adjusting medication doses, and assessing kidney function in various pediatric conditions. The Bedside Schwartz equation is specifically designed for children aged 1-18 years.

4. Using the Calculator

Tips: Enter height in centimeters and serum creatinine in mg/dL. Ensure measurements are recent and accurate. This calculator is validated for children aged 1-18 years. For infants under 1 year, consult pediatric nephrology specialists.

5. Frequently Asked Questions (FAQ)

Q1: What age range is this calculator appropriate for?
A: The Bedside Schwartz equation is validated for children aged 1-18 years. For infants under 1 year, different equations or direct measurement methods should be used.

Q2: Why is height used instead of weight in this equation?
A: Height serves as a better proxy for muscle mass and body surface area in children, which correlates more accurately with creatinine production and kidney function.

Q3: What are normal eGFR values in children?
A: Normal eGFR in children varies by age but generally ranges from 90-140 mL/min/1.73m². Values should be interpreted in the context of the child's age and clinical condition.

Q4: Are there limitations to the Bedside Schwartz equation?
A: The equation may be less accurate in children with extreme body habitus, muscle wasting, amputations, or rapidly changing kidney function. It should not be used in neonates.

Q5: How often should eGFR be monitored in children with kidney disease?
A: Monitoring frequency depends on the underlying condition and stability of kidney function. Children with stable CKD may require monitoring every 3-6 months, while those with acute changes may need more frequent assessment.