NKF Pediatric GFR Calculator

NKF Pediatric Equation:

\[ eGFR = 0.413 \times \frac{Height}{Scr} \]

Estimated GFR (eGFR):

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1. What is the NKF Pediatric GFR Equation?

The NKF (National Kidney Foundation) pediatric equation estimates glomerular filtration rate (GFR) in children using height and serum creatinine. This formula is specifically validated for pediatric populations and provides accurate assessment of kidney function in children.

2. How Does the Calculator Work?

The calculator uses the NKF Pediatric equation:

\[ eGFR = 0.413 \times \frac{Height}{Scr} \]

Where:

\( Height \) — Height in centimeters (cm)
\( Scr \) — Serum creatinine in milligrams per deciliter (mg/dL)
0.413 — Constant coefficient for pediatric calculation

Explanation: The equation accounts for the relationship between height, creatinine levels, and kidney function in pediatric patients, providing age-appropriate GFR estimation.

3. Importance of Pediatric eGFR Calculation

Details: Accurate GFR estimation in children is essential for detecting congenital kidney abnormalities, monitoring kidney development, diagnosing pediatric kidney diseases, and guiding appropriate medication dosing for pediatric patients.

4. Using the Calculator

Tips: Enter height in centimeters and serum creatinine in mg/dL. Ensure accurate height measurement and use recent creatinine values. All values must be valid (height > 0, creatinine > 0).

5. Frequently Asked Questions (FAQ)

Q1: What age range is this equation valid for?
A: The NKF pediatric equation is typically used for children aged 1-18 years, though specific validation may vary by study.

Q2: How do pediatric eGFR values differ from adults?
A: Normal eGFR values in children are generally higher than adults and vary by age, with infants having lower values that increase during childhood.

Q3: Why is height used in pediatric equations?
A: Height serves as a surrogate for body surface area in children, providing better correlation with kidney function than weight alone.

Q4: Are there limitations to this equation?
A: Less accurate in children with extreme body habitus, malnutrition, edema, or rapidly changing kidney function. Not validated for neonates.

Q5: When should this equation not be used?
A: Avoid in children with amputations, severe obesity, muscle wasting diseases, or when precise GFR measurement is clinically necessary.