NIDDK Pediatric GFR Calculator

NIDDK Pediatric Equation:

\[ eGFR = 0.413 \times \frac{Height}{Scr} \]

Estimated GFR (eGFR):

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1. What is the NIDDK Pediatric GFR Calculator?

The NIDDK Pediatric GFR Calculator uses the Bedside CKiD (Schwartz) equation to estimate glomerular filtration rate (GFR) in pediatric patients. This equation is specifically validated for children and provides accurate assessment of kidney function in the pediatric population.

2. How Does the Calculator Work?

The calculator uses the NIDDK Pediatric equation:

\[ eGFR = 0.413 \times \frac{Height}{Scr} \]

Where:

\( Height \) — Patient height in centimeters (cm)
\( Scr \) — Serum creatinine in milligrams per deciliter (mg/dL)
\( 0.413 \) — Constant coefficient specific to pediatric patients

Explanation: This equation accounts for the relationship between height, serum creatinine, and kidney function in children, providing age-appropriate GFR estimation.

3. Importance of Pediatric eGFR Calculation

Details: Accurate GFR estimation in children is essential for diagnosing and monitoring kidney disease, guiding treatment decisions, and adjusting medication dosages appropriate for pediatric patients.

4. Using the Calculator

Tips: Enter height in centimeters and serum creatinine in mg/dL. Both values must be positive numbers. Ensure measurements are recent and accurate for reliable results.

5. Frequently Asked Questions (FAQ)

Q1: What age range is this calculator appropriate for?
A: This calculator is specifically designed for pediatric patients, typically from infancy through adolescence (up to 18 years).

Q2: How does this differ from adult GFR equations?
A: Pediatric equations account for growth and development factors, using height as a key variable to normalize for body size differences in children.

Q3: What are normal eGFR values for children?
A: Normal eGFR values in children vary by age and body size, but generally range from 90-140 mL/min/1.73m², with higher values in younger children.

Q4: When should this calculator not be used?
A: This calculator may be less accurate in patients with extreme body composition, amputations, or rapidly changing kidney function.

Q5: Is fasting required for creatinine measurement?
A: While not always required, fasting samples provide more consistent results. Avoid testing after high-protein meals or strenuous exercise.