Kidney Health eGFR Calculator

Kidney Health eGFR Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What is the Kidney Health eGFR Equation?

The Kidney Health eGFR equation estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex. This specialized equation provides accurate assessment of kidney function for general kidney health monitoring.

2. How Does the Calculator Work?

The calculator uses the Kidney Health eGFR equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: The equation accounts for non-linear relationship between creatinine and GFR, with different coefficients for different demographic groups.

3. Importance of eGFR Calculation

Details: Accurate GFR estimation is crucial for monitoring kidney health, detecting early kidney dysfunction, and assessing overall renal function status.

4. Using the Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. All values must be valid (creatinine > 0, age between 1-120).

5. Frequently Asked Questions (FAQ)

Q1: What makes this equation different from CKD-EPI?
A: This equation uses optimized coefficients (142, -1.200, 0.9938) specifically calibrated for general kidney health assessment.

Q2: What are normal eGFR values?
A: Normal is generally ≥90 mL/min/1.73m², though values naturally decline with age. Values below 60 may indicate kidney impairment.

Q3: When is the best time to measure creatinine?
A: Morning fasting sample is ideal, but random samples are acceptable. Avoid testing after meat-heavy meals or vigorous exercise.

Q4: Are there limitations to this equation?
A: Less accurate in extremes of age/weight, amputees, pregnant women, and those with rapidly changing kidney function.

Q5: Can this be used for clinical decisions?
A: For clinical decisions, consult with healthcare professionals who may use additional tests and clinical context.