Kidney Function Test GFR Calculator

Kidney Function GFR Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What Is The Kidney Function Test GFR Calculator?

The Kidney Function Test GFR Calculator estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex. This specialized equation provides accurate assessment of kidney function for clinical evaluation and monitoring.

2. How Does The Calculator Work?

The calculator uses the Kidney Function GFR equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: This equation accounts for the non-linear relationship between serum creatinine levels and glomerular filtration rate, with optimized coefficients for different demographic groups.

3. Importance Of GFR Calculation

Details: Accurate GFR estimation is essential for detecting early kidney dysfunction, staging chronic kidney disease, monitoring disease progression, and guiding appropriate therapeutic interventions.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. Ensure all values are valid (creatinine > 0, age between 1-120 years) for accurate results.

5. Frequently Asked Questions (FAQ)

Q1: What Is The Normal Range For GFR?
A: Normal GFR is generally ≥90 mL/min/1.73m² in healthy adults, though values naturally decline with advancing age.

Q2: How Often Should GFR Be Measured?
A: Frequency depends on clinical context - annually for high-risk patients, more frequently for those with established kidney disease or during treatment changes.

Q3: What Factors Can Affect GFR Accuracy?
A: Muscle mass, diet, hydration status, certain medications, and acute illness can temporarily affect creatinine levels and GFR estimates.

Q4: When Is This Calculator Most Useful?
A: Ideal for routine kidney function screening, monitoring known kidney disease, and pre-operative assessments in adult populations.

Q5: Are There Patient Groups Where This Calculator May Be Less Accurate?
A: Accuracy may be reduced in extremes of age, amputees, highly muscular or malnourished individuals, and those with rapidly changing kidney function.