Kidney Foundation Calculator

Kidney Foundation Equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Estimated GFR (eGFR):

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1. What Is The Kidney Foundation Calculator?

The Kidney Foundation Calculator estimates glomerular filtration rate (GFR) using a specialized equation that incorporates serum creatinine, age, and gender. This tool provides accurate assessment of kidney function for clinical evaluation and monitoring.

2. How Does The Calculator Work?

The calculator uses the Kidney Foundation equation:

\[ eGFR = 142 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.200} \times 0.9938^{age} \times (1.012 \text{ if female}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.241 (female) or -0.302 (male)
\( age \) — Age in years
1.012 — Female multiplier

Explanation: This equation provides a refined estimation of kidney function by accounting for the non-linear relationship between serum creatinine levels and actual glomerular filtration rate.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is essential for detecting early kidney dysfunction, staging chronic kidney disease, monitoring disease progression, and adjusting medication dosages based on renal function.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. Ensure all values are valid with creatinine greater than 0 and age between 1-120 years for accurate results.

5. Frequently Asked Questions (FAQ)

Q1: How Does This Equation Differ From CKD-EPI?
A: The Kidney Foundation equation uses different coefficients (142 vs 141, different exponents) and may provide alternative estimation approaches for specific patient populations.

Q2: What Are Normal eGFR Values?
A: Normal glomerular filtration rate is generally ≥90 mL/min/1.73m², though values naturally decline with advancing age. Persistent values below 60 indicate chronic kidney disease.

Q3: When Is The Best Time To Measure Creatinine?
A: Morning fasting samples are preferred, though random samples are acceptable. Avoid testing shortly after high-protein meals or intense physical activity.

Q4: Are There Limitations To This Equation?
A: This equation may be less accurate in elderly patients, those with extreme body weights, amputees, pregnant women, and individuals with rapidly changing kidney function.

Q5: Can This Calculator Be Used For Drug Dosing?
A: While useful for estimation, precise drug dosing in critical situations may require measured GFR using gold-standard methods like iohexol clearance.