Historical eGFR Calculator

Historical eGFR Calculator - NIDDK NIH.Gov

Historical NIDDK eGFR using CKD-EPI 2009 with race:

\[ eGFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{Age} \times (1.018 \text{ if female}) \times (1.159 \text{ if Black}) \]

Serum Creatinine (Scr):

mg/dL

Age:

years

Gender:

Race:

Estimated GFR (eGFR):

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1. What Is Historical eGFR Calculator?

The Historical eGFR Calculator uses the CKD-EPI 2009 equation with race factor as originally developed by NIDDK NIH. This version represents the historical standard before race-free equations were implemented, providing continuity with older medical records and research data.

2. How Does The Calculator Work?

The calculator uses the Historical NIDDK CKD-EPI 2009 equation:

\[ eGFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{Age} \times (1.018 \text{ if female}) \times (1.159 \text{ if Black}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.329 (female) or -0.411 (male)
\( Age \) — Age in years
1.018 — Female multiplier
1.159 — Black race multiplier

Explanation: This historical equation includes race as a biological variable, reflecting the original 2009 CKD-EPI development cohort characteristics.

3. Importance Of eGFR Calculation

Details: Historical eGFR calculations are important for comparing current results with older medical records, understanding historical research data, and maintaining consistency in longitudinal patient monitoring.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, select gender and race. All values must be valid (creatinine > 0, age between 1-120). Note that this calculator uses the historical race-inclusive formula.

5. Frequently Asked Questions (FAQ)

Q1: Why Use The Historical Version?
A: For comparing with older medical records, research consistency, and understanding historical clinical decisions made using race-inclusive equations.

Q2: What Is The Difference From Current Equations?
A: Current guidelines recommend race-free equations, while this historical version includes the race multiplier factor as originally published.

Q3: When Should I Use This Calculator?
A: When reviewing historical data, comparing with older results, or for research purposes requiring the original equation format.

Q4: Are There Limitations To This Equation?
A: Yes, the race factor has been questioned for perpetuating health disparities, and modern practice favors race-free calculations.

Q5: Should This Be Used For Current Clinical Decisions?
A: For current patient care, consult latest clinical guidelines which typically recommend race-free eGFR equations.