1. What is the Original Schwartz Equation for Infants?

The Original Schwartz Equation is a validated formula for estimating glomerular filtration rate (GFR) in term infants from birth to 1 year of age. It uses height and serum creatinine to provide a reliable assessment of kidney function in this specific pediatric population.

2. How Does the Calculator Work?

The calculator uses the Original Schwartz equation for infants:

Where:

• \( Height \) — Infant height in centimeters (cm)
• \( Scr \) — Serum creatinine in milligrams per deciliter (mg/dL)
• 0.45 — Empirical constant specific for infants

Explanation: This simplified equation accounts for the linear relationship between height, creatinine, and GFR in infants, with the constant 0.45 derived from pediatric population studies.

3. Importance of Infant GFR Calculation

Details: Accurate GFR estimation in infants is essential for detecting congenital kidney abnormalities, monitoring kidney function in critically ill neonates, and guiding medication dosing in this vulnerable population.

4. Using the Calculator

Tips: Enter infant height in centimeters and serum creatinine in mg/dL. Ensure measurements are accurate and recent. This calculator is specifically validated for term infants from birth to 1 year of age.

5. Frequently Asked Questions (FAQ)

Q1: What age range is this equation valid for?
A: This equation is specifically validated for term infants from birth to 1 year of age.

Q2: Can this be used for preterm infants?
A: No, the Original Schwartz equation for infants is validated for term infants only. Preterm infants may require different equations or direct measurement methods.

Q3: What are normal eGFR values for infants?
A: Normal infant GFR values range from approximately 30-50 mL/min/1.73m² at birth, increasing rapidly during the first year of life.

Q4: How should infant height be measured?
A: For infants under 2 years, length should be measured in recumbent position using an infantometer for accuracy.

Q5: Are there limitations to this equation?
A: This equation may be less accurate in infants with extreme body composition, edema, or rapidly changing kidney function.