1. What Is The eGFR Equation?

The eGFR equation estimates glomerular filtration rate (GFR) from serum creatinine, age, and sex. It provides an accurate assessment of kidney function for clinical evaluation and monitoring.

2. How Does The Calculator Work?

The calculator uses the eGFR equation:

Where:

• \( Scr \) — Serum creatinine (mg/dL)
• \( \kappa \) — 0.7 (female) or 0.9 (male)
• \( \alpha \) — -0.241 (female) or -0.302 (male)
• \( age \) — Age in years
• 1.012 — Female multiplier

Explanation: The equation accounts for the non-linear relationship between creatinine and GFR, with different coefficients for different demographic groups.

3. Importance Of eGFR Calculation

Details: Accurate GFR estimation is essential for assessing kidney function, detecting chronic kidney disease, and guiding appropriate medical management and treatment decisions.

4. Using The Calculator

Tips: Enter serum creatinine in mg/dL, age in years, and select gender. All values must be valid (creatinine > 0, age between 1-120 years).

5. Frequently Asked Questions (FAQ)

Q1: What Is The Purpose Of This eGFR Equation?
A: This equation provides a reliable estimate of glomerular filtration rate based on serum creatinine, age, and gender for clinical assessment of kidney function.

Q2: What Are Normal eGFR Values?
A: Normal eGFR is generally ≥90 mL/min/1.73m². Values below 60 mL/min/1.73m² for 3+ months may indicate chronic kidney disease.

Q3: When Should Serum Creatinine Be Measured?
A: Morning fasting samples are ideal, but random samples are acceptable. Avoid testing immediately after high-protein meals or strenuous exercise.

Q4: Are There Limitations To This Equation?
A: The equation may be less accurate in extremes of age, body composition, pregnant women, and individuals with rapidly changing kidney function.

Q5: Can This Equation Be Used For Drug Dosing?
A: While useful for initial assessment, precise drug dosing may require measured GFR in specific clinical situations and populations.