Australian Kidney eGFR Calculator

Australian Kidney Health eGFR using CKD-EPI 2009:

\[ eGFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{Age} \times (1.018 \text{ if female}) \times (1.159 \text{ if Black}) \]

Serum Creatinine (Scr):

mg/dL

Age:

years

Gender:

Race:

Estimated GFR (eGFR):

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1. What is the Australian Kidney eGFR Calculator?

The Australian Kidney eGFR Calculator uses the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) 2009 equation to estimate glomerular filtration rate (GFR) from serum creatinine, age, sex, and race. This calculator is specifically adapted for Australian clinical practice and provides a more accurate assessment of kidney function than older equations.

2. How Does the Calculator Work?

The calculator uses the Australian Kidney Health eGFR equation:

\[ eGFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{Age} \times (1.018 \text{ if female}) \times (1.159 \text{ if Black}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.329 (female) or -0.411 (male)
\( Age \) — Age in years
1.018 — Female multiplier
1.159 — Black race multiplier

Explanation: This equation accounts for the non-linear relationship between creatinine and GFR, with different coefficients optimized for Australian population demographics.

3. Importance of eGFR Calculation

Details: Accurate GFR estimation is crucial for diagnosing chronic kidney disease in Australian patients, determining disease stage according to Australian guidelines, and guiding appropriate medication dosing in clinical practice.

4. Using the Calculator

Tips: Enter serum creatinine in mg/dL, age in years, select gender and race. All values must be valid (creatinine > 0, age between 1-120). This calculator follows Australian Kidney Health recommendations.

5. Frequently Asked Questions (FAQ)

Q1: Why use the Australian Kidney eGFR Calculator?
A: This calculator uses the CKD-EPI 2009 equation specifically validated for Australian populations, providing more accurate results for Australian patients compared to international versions.

Q2: What are normal eGFR values in Australia?
A: Normal eGFR is generally ≥90 mL/min/1.73m² in Australian adults, though values naturally decline with age. Values below 60 mL/min/1.73m² persisting for 3+ months indicate chronic kidney disease.

Q3: When should creatinine be measured in Australian practice?
A: Morning fasting samples are preferred in Australian laboratories, but random samples are acceptable for routine monitoring. Avoid testing after meat-heavy meals or vigorous exercise.

Q4: Are there limitations to this equation in Australia?
A: The equation may be less accurate in extremes of age/weight, amputees, pregnant women, and those with rapidly changing kidney function. Consult Australian nephrology guidelines for special populations.

Q5: Should this be used for drug dosing in Australia?
A: For precise drug dosing in Australian clinical practice, measured GFR may be needed in certain high-risk populations as per Australian therapeutic guidelines.